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Merck
CN

434625

Sigma-Aldrich

Leukotriene B₄

≥97% (HPLC), oil, proinflammatory agent, Calbiochem®

别名:

Leukotriene B4, LTB₄, 5(S),12(R)-Dihydroxy-6- cis-8- trans-10- trans-14- cis-eicosatetraenoic Acid

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关于此项目

经验公式（希尔记法）:
C20H32O4
CAS Number:
71160-24-2
分子量:
336.47
MDL编号:
MFCD00135630
UNSPSC代码:
12352211
NACRES:
NA.77

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Product Name

Leukotriene B4, Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium.

描述

Merck USA index - 14, 5455

质量水平

100

方案

≥97% (HPLC)

表单

oil

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

clear

溶解性

ethanol: soluble

运输

wet ice

储存温度

−70°C

SMILES字符串

OC(CCCC(=O)O)\C=C\C=C\C=C\C(O)C\C=C\CCCCC

InChI

1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6+,14-10+,15-11+

InChI key

VNYSSYRCGWBHLG-XUOUMLBJSA-N

相关类别

一般描述

Potent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.
Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.

生化/生理作用

Cell permeable: no
Primary Target
Polymorphonuclear leukocytes
Product does not compete with ATP.
Reversible: no

外形

In Ethanol.

制备说明

Following initial thaw, aliquot and freeze (-70°C).

其他说明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Kendall, A.P., et al. 1995. Anesthesia 50, 590.
Dokter, W.H., et al. 1994. Leukemia 8, 1181.
Jedlitschky, G., et al. 1991. J. Biol. Chem.266, 24763.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Flammable (J)

象形图

FlameExclamation mark
GHS02,GHS07

警示用语：

Danger

危险声明

H225,H319

危险分类

Eye Irrit. 2 - Flam. Liq. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 2

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