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Merck
CN

437694

Sigma-Aldrich

DL-α-Lipoic Acid, Dihydro-

≥95% (TLC), NO scavenger, liquid

别名:

DL-α-Lipoic Acid, Dihydro-, DHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-

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关于此项目

经验公式(希尔记法):
C8H16O2S2
CAS Number:
分子量:
208.34
MDL编号:
UNSPSC代码:
12352106
NACRES:
NA.77
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Product Name

DL-α-Lipoic Acid, Dihydro-, An effective antioxidant.

质量水平

方案

≥95% (TLC)

表单

liquid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

light yellow

溶解性

ethanol: 50 mg/mL

运输

ambient

储存温度

2-8°C

SMILES字符串

SC(CCS)CCCCC(=O)O

InChI

1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10)

InChI key

IZFHEQBZOYJLPK-UHFFFAOYSA-N

一般描述

An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α1-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.

生化/生理作用

Cell permeable: no
Primary Target
Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals
Product does not compete with ATP.
Reversible: no

包装

Packaged under inert gas

其他说明

Packer, L., et al. 1997. Adv. Pharmacol. 38, 79.
Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Irritant (B)

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

348.1 °F - Cleveland open cup

闪点(°C)

175.6 °C - Cleveland open cup


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