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444225

MMP-3 Inhibitor II

Name: MMP-3 Inhibitor II
Brand: MM

The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

别名:

MMP-3 Inhibitor II, N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH

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关于此项目

经验公式（希尔记法）:

C₁₃H₂₀N₂O₅S

化学文摘社编号:

161314-17-6

分子量:

316.37

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD02179370

Assay:

≥98% (TLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze

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属性

Quality Level

100

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white

solubility

DMSO: 30 mg/mL, ethanol: 8 mg/mL

shipped in

ambient

storage temp.

10-30°C

SMILES string

[S](=O)(=O)(N(CC(C)C)CC(=O)NO)c1ccc(cc1)OC

InChI

1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)

InChI key

JIRXORZYIXSWOB-UHFFFAOYSA-N

说明

General description

A cell-permeable, potent inhibitor of human MMP-3 (stromelysin; K_i = 130 nM).

A potent and cell-permeable inhibitor of human MMP-3 (K_i = 130 nM).

Biochem/physiol Actions

Cell permeable: yes

Primary Target
human MMP-3

Product does not compete with ATP.

Reversible: no

Target K_i: 130 nM against human MMP-3

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Kato, N., et al. 2002. Genome Informatics13, 272.
MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c