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Merck
CN

444244

MMP-2 Inhibitor I

The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

别名:

MMP-2 Inhibitor I, cis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy

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关于此项目

经验公式(希尔记法):
C18H35NO2
化学文摘社编号:
分子量:
297.48
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
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Quality Segment

assay

≥98% (HPLC)

form

solid

potency

1.7 mM Ki

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

DMSO: 2 mg/mL, ethanol: 3 mg/mL

shipped in

wet ice

storage temp.

−20°C

SMILES string

N(O)C(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(20)19-21/h9-10,21H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

InChI key

LTXHELLMCCEDJG-KTKRTIGZSA-N

General description

A cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (Ki = 1.7 µM).
Potent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (Ki = 1.7 µM)

Biochem/physiol Actions

Cell permeable: yes
Primary Target
MMP-2
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Preparation Note

Unstable in solution; reconstitute just prior to use.

Other Notes

Berton, A., et. al. 2001. J. Biol. Chem.276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci.878, 647.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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