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454565

Methyl Arachidonyl Fluorophosphonate - Calbiochem

Name: Methyl Arachidonyl Fluorophosphonate - Calbiochem
Brand: MM

别名:

Methyl Arachidonyl Fluorophosphonate - Calbiochem, MAFP, cPLA2α Inhibitor III

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关于此项目

经验公式（希尔记法）:

C₂₁H₃₆FO₂P

分子量:

370.48

UNSPSC Code:

12352200

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属性

assay

≥98% (TLC)

Quality Segment

100

form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

shipped in

wet ice

storage temp.

−70°C

说明

General description

This product has been discontinued.

A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A₂ (PLA₂) but not of secretory PLA₂.

A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A₂ (PLA₂) but not secretory PLA₂.

Biochem/physiol Actions

Cell permeable: no

Primary Target
calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)

Product does not compete with ATP.

Reversible: no

Physical form

In methyl acetate.

Preparation Note

Prior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.

Other Notes

Balsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta1302, 55.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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