assay
≥98% (TLC)
Quality Segment
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
wet ice
storage temp.
−70°C
General description
This product has been discontinued.
A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2) but not of secretory PLA2.
A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2) but not secretory PLA2.
Biochem/physiol Actions
Cell permeable: no
Primary Target
calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)
calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)
Product does not compete with ATP.
Reversible: no
Physical form
In methyl acetate.
Preparation Note
Prior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.
Other Notes
Balsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta1302, 55.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta1302, 55.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)