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产品名称
冈田酸,铵盐, Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.
SMILES string
[N+H4].[O-]C(=O)[C@](O)(C[C@H]1O[C@]2(O[C@@H](CC(=C2)C)[C@H](C)\C=C\[C@@H]3O[C@@]4(O[C@H]5[C@@H](C(=C)[C@H](OC5CC4)[C@@H](O)C[C@@H](C6O[C@]7(OCCCC7)CC[C@H]6C)C)O)CC3)[C@@H](CC1)O)C
InChI
1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1
InChI key
ZBOMSHVRJSJGNR-JBNKPAQWSA-N
assay
≥98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 1 mg/mL, DMSO: 20 mg/mL, ethanol: 20 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
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相关类别
General description
Biochem/physiol Actions
PP1,PP2A
Other Notes
Kiguchi, K., et al. 1994.Cell Growth Differentiation5, 995.
Ohaka, Y., et al. 1993.Biochem.Biophys.Res. Commun.197, 916.
Gopalakrishna, R., et al. 1992.Biochem.Biophys.Res. Commun.189, 950.
Kreienbuhl, P., et al. 1992.Blood80, 2911.
Normura, M., et al. 1992.Biochemistry31, 11915.
Song, Q., et al. 1992.J. Cell Physiol.153, 550.
Tada, T., et al. 1992.Immunopharmacol.24, 17.
Cohen, P., et al. 1990.Trends Biochem.Sci.15, 98.
Cohen, P., et al. 1989.Annu.Rev. Biochem.58, 453.
Cohen, P., and Cohen, P.T.W.1989.J. Biol. Chem.264, 21435.
Haystead, T.A.J., et al. 1989.Nature337, 78.
Legal Information
Disclaimer
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
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