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459618

Okadaic Acid potassium salt

Name: Okadaic Acid potassium salt
Brand: MM

≥95% (HPLC), solid, protein phosphatase 2A and protein phosphatase 1 inhibitor, Calbiochem^®

别名:

Okadaic Acid, Potassium Salt

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关于此项目

经验公式（希尔记法）:

C₄₄H₆₇O₁₃ · K

化学文摘社编号:

155751-72-7

分子量:

843.09

UNSPSC Code:

12352106

NACRES:

NA.77

MDL number:

MFCD00214356

Assay:

≥95% (HPLC)

Form:

solid

Storage condition:

OK to freeze, protect from light

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属性

产品名称

Okadaic Acid, Potassium Salt, Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.

Quality Segment

100

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

white

solubility

water: 1 mg/mL, DMSO: 20 mg/mL, ethanol: 20 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

[K+].[O-]C(=O)C(O)(CC1OC2(OC(CC(=C2)C)C(C)C=CC3OC4(OC5C(OC(C(=C)C5O)C(O)CC(C6OC7(OCCCC7)CCC6C)C)CC4)CC3)C(CC1)O)C

InChI

1S/C44H68O13.K/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);/q;+1/p-1

InChI key

UXRQUXBFVICHQJ-UHFFFAOYSA-M

说明

General description

Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.

Biochem/physiol Actions

Cell permeable: no

Primary Target
PP1, PP2

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 10-15 nM, 0.1 nM, against protein phosphatase 1 and protein phosphatase 2A, respectively

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Gjertsen, B.T., et al. 1994. J. Cell Sci.107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differ.5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun.197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun.189, 950.
Kreienbuhl, P., et al. 1992. Blood80, 2911.
Nomura, M., et al. 1992. Biochemistry31, 11915.
Song, Q., et al. 1992. J. Cell Physiol.153, 550.
Tada, Y., et al. 1992. Immunopharmacol.24, 17.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Toxic (F)

象形图

GHS06

警示词

Danger

危险代码

H301 + H311 + H331,H315

预防性声明

P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

怎么回事？

WGK 3

闪点 (F)

Not applicable

闪点 (°C)