Product Name
MG-132 in EtOH, ≥95% by HPLC, InSolution, ≥95%, reversible proteasome inhibitor
质量水平
方案
≥95% (HPLC)
表单
liquid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
protect from light
运输
ambient
储存温度
−70°C
一般描述
Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM).Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1) which initiates apoptosis. Inhibits NF-κBactivation (IC50 = 3 µM). This material is ≥95% pure by HPLC. A material with ≥98% purity by HPLC (Cat. No. 474791) and the solid form of this compound (Cat. No. 474787) are also available.
生化/生理作用
Cell permeable: yes
Ki = 4 nM for proteasomal inhibition
Reversible: yes
Secondary Target
IKK
IKK
包装
Packaged under inert gas
警告
Toxicity: Flammable (J)
重悬
Following initital thaw, aliquot and freeze (-70°C).
其他说明
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Eye Irrit. 2 - Flam. Liq. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
53.6 °F - closed cup - Information refers to the main ingredient.
闪点(°C)
12 °C - closed cup - Information refers to the main ingredient.
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