form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
solubility
aqueous buffer: soluble
shipped in
wet ice
storage temp.
−20°C
Quality Level
General description
重组人 β2-微球蛋白在N端与His•Tag序列融合并在大肠埃希菌中表达。随后用CNBr裂解以去除His•Tag序列。 一种与I类MHC分子的α-链非共价结合的细胞外蛋白。用作各种肿瘤和肾脏疾病的标志物。在淀粉样蛋白原纤维延伸的体外模型中,纯化的蛋白的功能类似于天然蛋白。
Preparation Note
初次融化后,等分并冷冻(-20°C)。
Analysis Note
通过 SDS-PAGE 获得单一条带
Other Notes
Sugg, S.V., et al. 1981.Proc.Natl.Acad.Sci. USA 78, 6613.
Berggard, I., and Bearn, G. 1968.J. Biol. Chem. 243, 4095.
Berggard, I., and Bearn, G. 1968.J. Biol. Chem. 243, 4095.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性:标准处理(A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Naomi Issler et al.
Journal of the American Society of Nephrology : JASN, 33(4), 732-745 (2022-02-13)
The endocytic reabsorption of proteins in the proximal tubule requires a complex machinery and defects can lead to tubular proteinuria. The precise mechanisms of endocytosis and processing of receptors and cargo are incompletely understood. EHD1 belongs to a family of
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