476475
PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated
The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Myr-N-RKRTLRRL-OH, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
assay
≥97% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
solubility
water: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC50 = 5 µM) in intact cells.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
PKC
PKC
Product does not compete with ATP.
Reversible: yes
Target IC50: 5 µM against protein kinase C
Packaging
Yes
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Other Notes
Myr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
Ward, N.E., and O’Brian, C.A. 1993. Biochemistry32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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