NF-κB SN50M, Cell-Permeable Inactive Control Peptide

An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys³⁶³ and Gly for Arg³⁶⁴ in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.

Cell permeable: no

Primary Target
an inactive control for SN50 peptide

Product does not compete with ATP.

Reversible: no

Yes

Supplied as a trifluoroacetate salt.

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.

H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH

Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.

Sold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Toxicity: Standard Handling (A)