产品名称
MILLIPLEX® Total Akt/mTOR磁珠11-Plex套件 - 胞信号多重检测, Premixed Akt/mTOR Total 11-Plex Cell Signaling Panel
Quality Segment
product line
Milliplex®
species reactivity
human
packaging
pkg of 1 ea
technique(s)
multiplexing: suitable
input
cell lysate
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
This panel targets total expression of key proteins in the PI3K/Akt/mTOR signaling pathway, which regulates cell growth, metabolism, and survival. It includes total levels of Akt isoforms, mTOR, PTEN, GSK3α/β, IRS1, IGF1R, IR, p70S6K, and RPS6. These proteins are frequently altered in cancer, diabetes, and neurodegenerative diseases.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 11 analytes in human, mouse, or rat cell lysate samples.
Analytes Included: Akt (Total), GSK3α (Total), GSK3β (Total), IGF-1R (Total), IR (total), IRS1 (Total), mTOR (Total), p70S6K (Total), PTEN (Total), RPS6 (Total), TSC2 (Total)
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™Control Assays).
Analytes Included: Akt (Total), GSK3α (Total), GSK3β (Total), IGF-1R (Total), IR (total), IRS1 (Total), mTOR (Total), p70S6K (Total), PTEN (Total), RPS6 (Total), TSC2 (Total)
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™Control Assays).
Features and Benefits
- Simultaneously detect total expression of 11 proteins in the PI3K/Akt/mTOR signaling pathway
- Includes Akt1, Akt2, Akt3, mTOR, PTEN, GSK3α/β, IRS1, IGF1R, IR, p70S6K, and RPS6
- Magnetic bead-based format ensures reproducibility and efficient processing
- Compatible with cell lysates from cancer, metabolic, and signaling studies
- Ideal for oncology, metabolism, and cell biology research
- Fast, convenient alternative to Western Blotting and immunoprecipitation procedures
Legal Information
Luminex is a registered trademark of Luminex Corporation
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
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警示词
Danger
危险代码
Hazard Classifications
Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2
WGK
WGK 2