487950
NOC-5
A nitric oxide (NO) donor.
别名:
NOC-5, 3-[2-Hydroxy-1-(1-methylethyl)-2-nitrosohydrazino]-1-propanamine
InChI
1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,12H,3-5,7H2,1-2H3
InChI key
WEHZRCACNLQADC-UHFFFAOYSA-N
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
color
white
solubility
0.1 M NaOH: soluble, water: soluble
shipped in
ambient
storage temp.
−20°C
Quality Level
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General description
A nitric oxide (NO) donor. A stable NO-amine complex that can spontaneously release two equivalents of NO in solution under physiological conditions without any cofactor. Half-life (t½) in PBS, pH 7.4 is 93 minutes at 22°C. Relatively stable in alkaline solution (pH ≥10.0).
Biochem/physiol Actions
Cell permeable: no
Primary Target
A nitric oxide (NO) donor
A nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
Other Notes
Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
signalword
Danger
hcodes
Hazard Classifications
Self-react. C
存储类别
5.2 - Organic peroxides and self-reacting hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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