487952
NOC-7
A nitric oxide (NO) donor similar to NOC-5 but with a much shorter half-life of NO release.
别名:
NOC-7, 3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine
InChI key
AXAGAUVQMYPYHM-UHFFFAOYSA-N
InChI
1S/C5H14N4O2/c1-6-4-3-5-8(2)9(11)7-10/h6,11H,3-5H2,1-2H3
assay
≥90% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
color
white
solubility
0.1 M NaOH: soluble, water: soluble
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Half-life (t½) in PBS, pH 7.4 is 10 minutes at 22°C. Useful as a short-acting nitrovasodilator. Relatively stable in alkaline solution (pH ≥10.0).
Biochem/physiol Actions
Cell permeable: no
Primary Target
A nitric oxide (NO) donor
A nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O jut prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
Other Notes
Zhang, P., et al. 1996. Circulation94, 2235.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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