description
RTECS - MD0905000
Quality Level
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
clear colorless
CMC
50 - 300 μM
solubility
water: 25 mg/mL, aqueous buffer: soluble
density
1.06 g/mL
application(s)
(Isolating membrane proteins)
shipped in
ambient
storage temp.
15-25°C
SMILES string
O(CCOc1ccc(cc1)CCCCCCCCC)CCO
InChI
1S/C19H32O3/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)22-17-16-21-15-14-20/h10-13,20H,2-9,14-17H2,1H3
InChI key
BLXVTZPGEOGTGG-UHFFFAOYSA-N
General description
一种用于分离和纯化功能性膜蛋白复合物和双向（2D）凝胶电泳的非离子表面活性剂。与NP-40和TRITON ™X-100洗涤剂（目录号648462）的用法相似。
Application
NP-40 Alternative has been used:
- as a component of the lysis buffer for solubilizing proteins from transfected HEK293 cells.
- as a component of the wash buffer for efficient solubilization of biotinylated plasma proteins in plasma protein profiling and chromatin immunoprecipitation (ChIP).
- for the purification of doublet microtubules from cilia for single particle cryo-electron microscopy (cryo-EM).
Other Notes
Ripoche, P., et al. 1982.Biochim.Biophys.Acta693, 497.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow
Disclaimer
毒性：刺激性（B）
存储类别
11 - Combustible Solids
flash_point_f
503.6 °F - Pensky-Martens closed cup - (own results)
flash_point_c
262 °C - Pensky-Martens closed cup - (own results)
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - ED ENV 1 - Eye Irrit. 2 - Skin Irrit. 2
法规信息
监管及禁止进口产品
此项目有
Gustav Roder et al.
European journal of immunology, 39(10), 2682-2694 (2009-09-04)
Tapasin (Tpn) is an ER chaperone that is uniquely dedicated to MHC-I biosynthesis. It binds MHC-I molecules, integrates them into peptide-loading complexes, and exerts quality control of the bound peptides; only when an "optimal peptide" is bound will the MHC-I
Matthew R Miller et al.
Journal of biological methods, 2(3), e23-e23 (2015-10-13)
Over the past two decades, researchers have struggled to efficiently express foreign DNA in primary macrophages, impeding research progress. The applications of lipofection, electroporation, microinjection, and viral-mediated transfer typically result in disruptions in macrophage differentiation and function, low expression levels
Ying Zhang et al.
Cancer research, 79(19), 4994-5007 (2019-08-09)
Human astrocytomas and oligodendrogliomas are defined by mutations of the metabolic enzymes isocitrate dehydrogenase (IDH) 1 or 2, resulting in the production of the abnormal metabolite D-2 hydroxyglutarate. Here, we studied the effect of mutant IDH on cell proliferation and
Romina Fornes et al.
Scientific reports, 7(1), 8066-8066 (2017-08-16)
Pregnant women with polycystic ovary syndrome (PCOS) are often overweight or obese. To study the effects of maternal androgen excess in obese dams on metabolism, placental function and fetal growth, female C57Bl6J mice were fed a control (CD) or a
Peiwei Liu et al.
The Journal of cell biology, 219(6) (2020-04-30)
Mutations in the channel protein PKD2 cause autosomal dominant polycystic kidney disease, but the function of PKD2 in cilia remains unclear. Here, we show that PKD2 targets and anchors mastigonemes, filamentous polymers of the glycoprotein MST1, to the extracellular surface
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 492016-100ML | 07790788050832 |
| 492016-1000ML | 04055977273489 |
| 492016-500ML | 04055977273496 |
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