SMILES string
O(CCOc1ccc(cc1)CCCCCCCCC)CCO
InChI
1S/C19H32O3/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)22-17-16-21-15-14-20/h10-13,20H,2-9,14-17H2,1H3
InChI key
BLXVTZPGEOGTGG-UHFFFAOYSA-N
description
RTECS - MD0905000
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
clear colorless
CMC
50 - 300 μM
solubility
water: 25 mg/mL
aqueous buffer: soluble
density
1.06 g/mL
application(s)
(Isolating membrane proteins)
shipped in
ambient
storage temp.
15-25°C
Quality Level
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow
Other Notes
Ripoche, P., et al. 1982.Biochim.Biophys.Acta693, 497.
Disclaimer
毒性：刺激性（B）
General description
一种用于分离和纯化功能性膜蛋白复合物和双向（2D）凝胶电泳的非离子表面活性剂。与NP-40和TRITON ™X-100洗涤剂（目录号648462）的用法相似。
Application
NP-40 Alternative has been used:
- as a component of the lysis buffer for solubilizing proteins from transfected HEK293 cells.
- as a component of the wash buffer for efficient solubilization of biotinylated plasma proteins in plasma protein profiling and chromatin immunoprecipitation (ChIP).
- for the purification of doublet microtubules from cilia for single particle cryo-electron microscopy (cryo-EM).
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
监管及禁止进口产品
此项目有
Gustav Roder et al.
European journal of immunology, 39(10), 2682-2694 (2009-09-04)
Tapasin (Tpn) is an ER chaperone that is uniquely dedicated to MHC-I biosynthesis. It binds MHC-I molecules, integrates them into peptide-loading complexes, and exerts quality control of the bound peptides; only when an "optimal peptide" is bound will the MHC-I
Ju Gao et al.
Autophagy, 12(4), 632-647 (2016-04-07)
During proteasomal stress, cells can alleviate the accumulation of polyubiquitinated proteins by targeting them to perinuclear aggresomes for autophagic degradation, but the mechanism underlying the activation of this compensatory pathway remains unclear. Here we report that PINK1-s, a short form
Deyi Zhang et al.
Autophagy, 12(9), 1447-1459 (2016-06-16)
Macroautophagy/autophagy is a conserved catabolic process that recycles cytoplasmic material during low energy conditions. BECN1/Beclin1 (Beclin 1, autophagy related) is an essential protein for function of the class 3 phosphatidylinositol 3-kinase (PtdIns3K) complexes that play a key role in autophagy
Ying Zhang et al.
Cancer research, 79(19), 4994-5007 (2019-08-09)
Human astrocytomas and oligodendrogliomas are defined by mutations of the metabolic enzymes isocitrate dehydrogenase (IDH) 1 or 2, resulting in the production of the abnormal metabolite D-2 hydroxyglutarate. Here, we studied the effect of mutant IDH on cell proliferation and
Romina Fornes et al.
Scientific reports, 7(1), 8066-8066 (2017-08-16)
Pregnant women with polycystic ovary syndrome (PCOS) are often overweight or obese. To study the effects of maternal androgen excess in obese dams on metabolism, placental function and fetal growth, female C57Bl6J mice were fed a control (CD) or a
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