494459
n-Octyl-β-D-glucopyranoside
CAS 29836-26-8 is a non-ionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles.
别名:
n-Octyl-β-D-glucopyranoside, OG, n-Octylglucoside
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关于此项目
经验公式（希尔记法）:
C14H28O6
化学文摘社编号:
分子量:
292.37
UNSPSC Code:
12161902
NACRES:
NA.21
MDL number:
产品名称
n-Octyl-β-D-glucopyranoside, CAS 29836-26-8 is a non-ionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles.
SMILES string
O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)OCCCCCCCC
InChI
1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
InChI key
HEGSGKPQLMEBJL-RKQHYHRCSA-N
assay
≥98% (HPLC)
form
solid
mol wt
292.38 g/mol
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
aggregation number
84
impurities
≤0.05% n-octanol
≤35 mg/dL glucose
color
white
CMC
20 - 25 mM
mp
106.8 °C (at 984 hPa)
solubility
water: 100 mg/mL
shipped in
ambient
storage temp.
15-25°C
Quality Level
Application
- Tube-gel digestion: a novel proteomic approach for high throughput analysis of membrane proteins.: This article introduces a new method for analyzing membrane proteins using tube-gel digestion, which employs n-Octyl-β-D-glucopyranoside for effective solubilization of membrane proteins. This approach enhances the throughput and efficiency of proteomic analyses (Lu et al., 2005).
- Mixed micellization of a nonionic-cationic surfactant system constituted by n-octyl-beta-D-glucopyranoside/dodecyltrimethylammonium bromide/H2O.: The study explores the micellization behavior of a nonionic-cationic surfactant system involving n-Octyl-β-D-glucopyranoside and its interactions. The findings are significant for understanding surfactant properties and applications in biochemical processes (del Burgo et al., 2004).
Disclaimer
Toxicity: Standard Handling (A)
General description
Absorbance (10%, H2O, 260 nm):≤0.3.
Non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. Its well–defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.
Nonionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles. Its well-defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.
Other Notes
Hoshino, T., et al. 1992. J. Biol. Chem.267, 21313.
Levy, D., et al. 1992. Biochim. Biophys. Acta1107, 283.
Nunn, R.S., et al. 1992. J. Mol. Biol.228, 1259.
Lorber, B., et al. 1990. Biochim. Biophys. Acta1023, 254.
Jopski, B., et al. 1989. Biochim. Biophys. Acta978, 79.
Camm, E.L., et al. 1981. Plant Physiol.67, 1061.
Gould, R.J., et al. 1981. Biochemistry20, 6776.
Levy, D., et al. 1992. Biochim. Biophys. Acta1107, 283.
Nunn, R.S., et al. 1992. J. Mol. Biol.228, 1259.
Lorber, B., et al. 1990. Biochim. Biophys. Acta1023, 254.
Jopski, B., et al. 1989. Biochim. Biophys. Acta978, 79.
Camm, E.L., et al. 1981. Plant Physiol.67, 1061.
Gould, R.J., et al. 1981. Biochemistry20, 6776.
Preparation Note
Following reconstitution, store in the refrigerator (4°C), under sterile conditions. Aqueous stock solutions are stable for up to 3 months at 4°C. Solutions are susceptible to hydrolysis (especially acidic solutions) and enzymatic hydrolysis.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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