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Merck
CN

497985

Ornithine Decarboxylase Inhibitor, POB - Calbiochem

别名:

N-(4ʹ-Pyridoxyl)-Ornithine(BOC)-OMe, ODC Inhibitor, POB, Ornithine Decarboxylase Inhibitor, POB - Calbiochem

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关于此项目

线性分子式:
C19H31N3O6
NACRES:
NA.28
UNSPSC Code:
12352200
Form:
(White to off-white solid)
Quality level:
Storage condition:
OK to freeze
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form

(White to off-white solid)

Quality Level

storage condition

OK to freeze

solubility

soluble (H2O (1 mg/ml))

storage temp.

2-8°C

General description

A cell-permeable pyridoxyl-ornithine compound that acts as an effective analog of the transition state coenzyme-substrate adduct during orthithine decarboxylase- (ODC) catalyzed conversion of L-orthithine to Pultrescine. POB is typically 5- to 10-fold more potent than DFMO (Cat. No. 288500) in inhibiting intracellular ODC activity and tumor cell growth in cultures, while exhibiting little effect against the growth of nontumorigenic human aortic smooth muscle cells.




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全球贸易项目编号

货号GTIN
497985-10MG04055977199888