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Merck
CN

5.00469

S107

≥98% (HPLC), solid, RyR-Calstabin interaction stabilizer, Calbiochem®

别名:

RyR-Calstabin Interaction Stabilizer, S107, 7-methoxy-4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine, Ryanodine Receptor Stabilizer, Rycal S107

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关于此项目

经验公式(希尔记法):
C11H15NOS
化学文摘社编号:
分子量:
209.31
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
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产品名称

RyR-Calstabin Interaction Stabilizer, S107,

assay

≥98% (HPLC)

Quality Segment

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

off-white

solubility

DMSO: 100 mg/mL

storage temp.

2-8°C

SMILES string

S1CCN(Cc2c1ccc(c2)OC)C

InChI key

BGVCEGVSQDOGSB-UHFFFAOYSA-N

General description

RyR-Calstabin Interaction Stabilizer, S107 can protect hippocampal neurons from GABAergic synaptic changes caused by Abeta42 oligomers.

Application

RyR-Calstabin Interaction Stabilizer, S107 has been used in culture media for hypoxic exposures to study the impact of hypoxia on sarcoplasmic reticulum calcium leakage and expression of ryanodine receptor2 (RyR2).

Biochem/physiol Actions

Primary Target
RyR2

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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