InhibitorSelect TLR Signaling Pathway Panel

A panel containing 16 potent, selective and cell-permeable inhibitors that is useful for the study of TLR signaling: 1 mg of TIRAP Inhibitor Peptide, Cell-Permeable (>Cat. No. 613570), 10 mg of IL-1R Antagonist (>Cat. No. 407616), 5 mg of Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor (Cat. No. 407601), 1 mg of (5Z)-7-Oxozeaenol, Curvularia sp. (Cat. No. 499610), 10 mg of BX-795 (Cat. No. 204001), 5 mg of NBD-Binding Peptide II, Cell Permeable, CTP-NBD (Cat. No. 480026), 25 mg of Cdc42/Rac1 GTPase Inhibitor, ML141 (Cat. No. 217708), 5 mg of PKR Inhibitor (Cat. No. 527450), 5 mg of LY294002 (Cat. No. 440202), 5 mg of U0126 (Cat. No. 662005), 1 mg of IKK Inhibitor VII (Cat. No. 401486), 10 mg of BAY 11-7082 (Cat. No. 196870), 1 mg of SB 203580 (Cat. No. 559389), 5 mg of SP600125 (Cat. No. 420119), 10 mg of STAT3 Inhibitor III, WP1066 (Cat. No. 573097), and 10 mg of MG-132 (Cat. No. 474787). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817).

Cell permeable: yes

Primary Target
Major hubs involved in TLR signaling cascade

Packaged under inert gas

Following reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.

Please refer to information provided on the CD for reconstitution information of individual inhibitors.

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Wong, C.K., et al. 2007. Am. J. Respir. Cell Mol. Biol.37, 85.
Kawai, T. and Akira, S., 2007. Trends Mol. Med.13, 460.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Toxicity: Irritant (B)