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5.04820

Cinnabarinic acid

Name: Cinnabarinic acid
Brand: MM

别名:

Cinnabarinic acid, 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid

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关于此项目

经验公式（希尔记法）:

C₁₄H₈N₂O₆

化学文摘社编号:

606-59-7

分子量:

300.22

UNSPSC Code:

12352106

NACRES:

NA.77

MDL number:

MFCD18379297

Form:

solid

Assay:

≥98% (HPLC)

Solubility:

DMSO: 25 mM

Color:

red

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属性

assay

≥98% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

red

solubility

DMSO: 25 mM

storage temp.

−20°C

SMILES string

Nc1[c](cc2[o]c3c(nc2c1C(=O)O)c(ccc3)C(=O)O)=O

InChI

1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)

InChI key

FSBKJYLVDRVPTK-UHFFFAOYSA-N

说明

General description

A partial, low-potency agonist highly selective for mGlu₄ receptors (EC₅₀ >100 µM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu₄ receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication.

Biochem/physiol Actions

Primary Target
mGlu₄ receptors

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Slight warming is required for complete solubilization.

Other Notes

Fazio, Francesco, et al. 2012. Mol. Pharmacol.81, 643.

Volpi, C., et al. 2012. Neuropharmacol.63, 501.
Hiramatsu, R., et al. 2008. J. Cell Biochem.103, 42.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c