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5.04841

5,7-Dichlorokynurenic Acid, Sodium Salt

Name: 5,7-Dichlorokynurenic Acid, Sodium Salt
Brand: MM

别名:

5,7-Dichlorokynurenic Acid, Sodium Salt, 5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic acid sodium salt, DCKA

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关于此项目

经验公式（希尔记法）:

C₁₀H₄Cl₂NNaO₃

化学文摘社编号:

1184986-70-6

分子量:

280.04

MDL number:

MFCD00674925

UNSPSC Code:

12352106

NACRES:

NA.77

Assay:

≥99% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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属性

assay

≥99% (HPLC)

Quality Level

100

form

solid

potency

79 nM K_i

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

white

solubility

water: 10 mM, 1 M NaOH: 100 mM

storage temp.

2-8°C

SMILES string

[Na+].Clc1c2c(nc(cc2O)C(=O)[O-])cc(c1)Cl

InChI

1S/C10H5Cl2NO3.Na/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14;/h1-3H,(H,13,14)(H,15,16);/q;+1/p-1

InChI key

VPRPMJHKWHCUFW-UHFFFAOYSA-M

说明

General description

A very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (K_i = 79 nM vs. [3H]-glycine).

Biochem/physiol Actions

Primary Target
NMDA receptors

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Baron, B., et al. 1991. Eur. J. Pharmacol.206, 149.
Baron, B., et al. 1990. Mol. Pharmacol.38, 554.
Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res.18, 91.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c