5.05016
CX546
别名:
CX546, AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546
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关于此项目
经验公式（希尔记法）:
C14H17NO3
化学文摘社编号:
分子量:
247.29
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
SMILES string
N3(CCCCC3)C(=O)c1cc2c(cc1)OCCO2
InChI
1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2
InChI key
LJUNPHMOGNFFOS-UHFFFAOYSA-N
assay
≥98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
off-white
solubility
DMSO: soluble
Quality Level
General description
A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation.
Biochem/physiol Actions
Primary Target
AMPA
AMPA
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Silverman, L., et al. 2013. Neuropharmacol.64, 268.
Peleg-Raibstein, D., et al. 2012. Curr. Antipsych.2012, 361.
Schitine, C., et al. 2012. Eur. J. Neurosci.35, 1672.
Lipina, T., et al. 2006. Neuropsychopharmacology.32, 745.
Arai, C., et al. 2004. Neurosci.123, 1011.
Nagarajan, N., et al. 2001. Neuropharmacol.41, 650.
Peleg-Raibstein, D., et al. 2012. Curr. Antipsych.2012, 361.
Schitine, C., et al. 2012. Eur. J. Neurosci.35, 1672.
Lipina, T., et al. 2006. Neuropsychopharmacology.32, 745.
Arai, C., et al. 2004. Neurosci.123, 1011.
Nagarajan, N., et al. 2001. Neuropharmacol.41, 650.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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