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5.05222

RuBi-Nicotine

Name: RuBi-Nicotine
Brand: MM

别名:

RuBi-Nicotine, Bis(2,2′-bipyridine-N,N′)bis(S-nicotine-N1) ruthenium(2+) dichloride complex Bis(2,2ʹ-bipyridine-N,Nʹ)bis(S-nicotine-N1) ruthenium(2+) dichloride complex , Nicotinic Cholinergic Receptor Agonist, RuBi-Nicotine, nAChR Receptor Agonist, RuBi-Nico

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关于此项目

经验公式（希尔记法）:

C₄₀H₄₄Cl₂N₈Ru

化学文摘社编号:

1256362-30-7

分子量:

808.81

MDL number:

MFCD22989497

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥98% (NMR)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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属性

assay

≥98% (NMR)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

deep orange

solubility

methanol: 100 mM

storage temp.

−20°C

SMILES string

[Ru+2]85([NH]9=CC=CC=C9C%10=CC=CC=[NH]%108)([NH]6=CC=CC=C6C7=CC=CC=[NH]75)([NH]3=CC=CC(=C3)[C@H]4N(CCC4)C)[NH]1=CC=CC(=C1)[C@H]2N(CCC2)C.[Cl-].[Cl-]

InChI

1S/2C10H14N2.2C10H8N2.2ClH.Ru/c2*1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*1-3-7-11-9(5-1)10-6-2-4-8-12-10;;;/h2*2,4,6,8,10H,3,5,7H2,1H3;2*1-8H;2*1H;/q;;;;;;+2/p-2/t2*10-;;;;;/m00...../s1

InChI key

BQXVYFYPLMVART-ZPFSJBFKSA-L

说明

General description

A highly water soluble Ruthenium-bisbipyridine-caged nicotine that can be un-caged by blue and green light. Rapid nicotine release (<20 ns) and fast biological effects in vivo.

Biochem/physiol Actions

Primary Target
nAChR

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Filevich, O., et al. 2010. J. Inorg. Biochem.104, 51.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Toxic (F)

pictograms

GHS06,GHS09

signalword

Danger

pcodes

P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c