5.05816
Xanomeline Oxalate
≥99% (HPLC), muscarinic acetylcholine receptor (mAChR) subtype M1 agonist, solid
别名:
Xanomeline Oxalate, 3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole, Muscarinic Acetylcholine Receptor (mAChR) Agonist, Xanomeline
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H23N3OS · xC2H2O4
化学文摘社编号:
分子量:
281.42 (free base basis)
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥99% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, protect from light
产品名称
Xanomeline Oxalate,
storage temp.
2-8°C
SMILES string
[s]1nc(c(n1)C2=CCCN(C2)C)OCCCCCC.OC(=O)C(=O)O
InChI
1S/C14H23N3OS.C2H2O4/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12;3-1(4)2(5)6/h8H,3-7,9-11H2,1-2H3;(H,3,4)(H,5,6)
InChI key
ZJOUESNWCLASJP-UHFFFAOYSA-N
assay
≥99% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
off-white
solubility
DMSO: 10 mM, ethanol: 25 mM
Quality Level
General description
An agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC50 = 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer′s disease and schizophrenia.
Other Notes
Wang, D., et al., 2011. Biochem. Biophys. Res. Commun.410, 229.
Si, W., et al., 2010. Neurosci. Lett.473, 115.
Stanhope, et al., 2001. J. Exp. Pharmacol. Ther.299, 782.
Si, W., et al., 2010. Neurosci. Lett.473, 115.
Stanhope, et al., 2001. J. Exp. Pharmacol. Ther.299, 782.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持