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Merck
CN

5.05818

Scopolamine Hydrobromide

≥99% (HPLC), mAChR antagonist, solid

别名:

Scopolamine Hydrobromide, Muscarinic Acetylcholine Receptor (mAChR) Antagonist, Scopolamine, Levo-duboisine, Hyoscine, Scopoderm

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关于此项目

经验公式(希尔记法):
C17H21NO4 · xHBr
化学文摘社编号:
分子量:
303.35 (free base basis)
MDL number:
UNSPSC Code:
12352116
NACRES:
NA.77
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产品名称

Scopolamine Hydrobromide,

SMILES string

[Br].N1([C@@H]2[C@@H]3O[C@@H]3[C@@H]1CC(C2)OC(=O)[C@H](CO)c4ccccc4)C

InChI

1S/C17H21NO4.Br/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;/t11?,12-,13+,14+,15-,16+;/m1./s1

InChI key

XUZPYCBMTSSDHK-AKTDCHNFSA-N

assay

≥99% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

H2O: 100 mM

storage temp.

2-8°C

Quality Level

Disclaimer

Toxicity: Harmful (C)

General description

A competitive, non-selective antagonist for muscarinic acetylcholine receptors (mAChR). Most effective at treating motion sickness. It is also a research tool for inducing memory impairment in vivo. Frequently used in researches related to learning, memory and Alzheimer′s dementia.

Other Notes

Klinkenberg, I., et al. 2010. Neurosci Biobehav Rev34, 1307.
Aparkes. W. 1995. Psychopharmacologia.7, 1.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

存储类别

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

法规信息

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