assay
≥98% (HPLC)
form
powder
potency
3 μM IC50
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 10 mg/mL
storage temp.
−20°C
Quality Level
General description
A dibenzofuran conjugated peptidomimetic (13-mer) that acts as an allosteric inhibitor of galectin-1 binding to cell surface glycans (IC50 = 3 µM). Shown to reduce the proliferation of endothelial cells and reduce vessel density in murine tumor models.
Biochem/physiol Actions
Primary Target
Galectin-1
Galectin-1
Reversible: yes
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Dings, R.P., et al, 2013, J. Pharm. Exp. Ther.344, 589.
SVQMKNva-[DBF]-IIVKLNA
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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