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About This Item
经验公式（希尔记法）:
C16H17NO2 · xHCl
CAS Number:
分子量:
255.31 (free base basis)
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77
方案
≥98% (HPLC)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
water: 100 mM
储存温度
−20°C
SMILES字符串
Cl.N1C[C@@H](c3c(cc(c(c3)O)O)CC1)c2ccccc2
InChI
1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H/t14-;/m1./s1
InChI key
YEWHJCLOUYPAOH-PFEQFJNWSA-N
一般描述
A benzazepine derivative that acts as a selective Dopamine D1/D5 receptor partial agonist. Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer. The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity. Reported to have stimulant and anorectic effects.
生化/生理作用
Primary Target
D₁
D₁
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Trampus, M. et al. 1993. J. Pharmacol.235, 83.
Cooper, S. J. et al. 1990. Psychopharmacol.100, 182.
Dubois, A. et al. 1986. Neurosci.19, 125.
Kaiser, C. C. et al. 1982. J. Med. Chem.25, 697.
Cooper, S. J. et al. 1990. Psychopharmacol.100, 182.
Dubois, A. et al. 1986. Neurosci.19, 125.
Kaiser, C. C. et al. 1982. J. Med. Chem.25, 697.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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