5.06135
Venlafaxine Hydrochloride
别名:
Venlafaxine Hydrochloride, SERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
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关于此项目
经验公式（希尔记法）:
C17H27NO2 · xHCl
化学文摘社编号:
分子量:
277.40 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
SMILES string
[Cl-].N(CC(C2(CCCCC2)O)c1ccc(cc1)OC)(C)C.[H+]
InChI
1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
InChI key
QYRYFNHXARDNFZ-UHFFFAOYSA-N
assay
≥99% (HPLC)
form
solid
potency
82 nM Ki
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
white
solubility
water: 100 mM
DMSO: 50 mM
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Primary Target
SERT/NET
SERT/NET
Disclaimer
Toxicity: Standard Handling (A)
General description
A dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
Other Notes
Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci.2, 22.
Aboelwafa, A., et al. 2010. AAPS PharmSciTech.11, 1026.
Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry.97, 729.
Aboelwafa, A., et al. 2010. AAPS PharmSciTech.11, 1026.
Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry.97, 729.
Packaging
Packaged under inert gas
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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