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5.08017

nor-Binaltorphimine Dihydrochloride

Name: nor-Binaltorphimine Dihydrochloride
Brand: MM

≥98% (HPLC), solid, κ-opioid receptor antagonist, Calbiochem

别名:

nor-Binaltorphimine Dihydrochloride, Norbinaltorphimine, nor-BNI, κ Opioid Receptor Antagonist, nor-Binaltorphimine

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关于此项目

经验公式（希尔记法）:

C₄₀H₄₃N₃O₆ · 2HCl

化学文摘社编号:

105618-26-6

分子量:

734.71

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00069374

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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属性

产品名称

nor-Binaltorphimine Dihydrochloride,

assay

≥98% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

white to off-white

solubility

water: 50 mM

storage temp.

−20°C

SMILES string

N21CC3(C4(C(Oc%12c4c(ccc%12O)CC2C%13CC%13)c5[nH]c6c(c5C3)CC7(C98C6Oc%10c9c(ccc%10O)CC(N(C7)CC8)C%11CC%11)O)CC1)O

InChI

1S/C40H43N3O6/c44-27-7-5-21-13-25(19-1-2-19)42-11-9-39-29(21)33(27)48-35(39)31-23(15-37(39,46)17-42)24-16-38(47)18-43-12-10-40(38)30-22(14-26(43)20-3-4-20)6-8-28(45)34(30)49-36(40)32(24)41-31/h5-8,19-20,25-26,35-36,41,44-47H,1-4,9-18H2

InChI key

GYEXSFKLGQBRBJ-UHFFFAOYSA-N

说明

General description

A potent antagonist highly selective for κ opioid receptor with no effect on µ- or &delta- opioid receptors. Widely used in studies related to pain, addition, anxiety, depression, and sleep.

Biochem/physiol Actions

Primary Target
kappa opioid receptor

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Kishioka, S., et al. 2013. Neurosci. Letters.In press.

Valdez, G., et al. 2012. Pharma. Biochem. and Behavior.102, 44.
Takemori AE et al. 1988. J. Pharmacol. Exp. Ther.246, 255.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c