5.08160
DPDPE
别名:
DPDPE, δ Opioid Receptor Agonist, DPDPE
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关于此项目
经验公式（希尔记法）:
C30H39N5O7S2
化学文摘社编号:
分子量:
645.79
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Form:
solid
Assay:
≥99% (HPLC)
Solubility:
water: 1 mg/mL
Color:
off-white
assay
≥99% (HPLC)
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
off-white
solubility
water: 1 mg/mL
storage temp.
−20°C
SMILES string
S1SC([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C1(C)C)C(=O)O)Cc3ccccc3)NC(=O)[C@@H](N)Cc2ccc(cc2)O)(C)C
InChI
1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1
InChI key
MCMMCRYPQBNCPH-WMIMKTLMSA-N
General description
A potent agonist selective for δ opioid receptor (EC50 = 5.2 nM). Exhibits anti-convulsant effects in vivo in rats, also used in nociceptive studies.
Biochem/physiol Actions
Primary Target
δ opioid receptor
δ opioid receptor
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Chen, C., 1997. J. Pharmacol. Exp. Ther.283, 1151.
Chandrakumar, S., et al., 1992. J. Med. Chem.35, 2928.
Tortella, F. 1988. Peptides.9, 1177.
Clark, A., et al., 1986. Eur. J. Pharmacol.128, 303.
Chandrakumar, S., et al., 1992. J. Med. Chem.35, 2928.
Tortella, F. 1988. Peptides.9, 1177.
Clark, A., et al., 1986. Eur. J. Pharmacol.128, 303.
Tyr-D-Pen-Gly-Phe-D-Pen (2-5 disulfide bond)
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable