5.08160
DPDPE
别名:
DPDPE, δ Opioid Receptor Agonist, DPDPE
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关于此项目
经验公式（希尔记法）:
C30H39N5O7S2
化学文摘社编号:
分子量:
645.79
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
SMILES string
S1SC([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C1(C)C)C(=O)O)Cc3ccccc3)NC(=O)[C@@H](N)Cc2ccc(cc2)O)(C)C
InChI
1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1
InChI key
MCMMCRYPQBNCPH-WMIMKTLMSA-N
assay
≥99% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
off-white
solubility
water: 1 mg/mL
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Primary Target
δ opioid receptor
δ opioid receptor
Disclaimer
Toxicity: Standard Handling (A)
General description
A potent agonist selective for δ opioid receptor (EC50 = 5.2 nM). Exhibits anti-convulsant effects in vivo in rats, also used in nociceptive studies.
Other Notes
Chen, C., 1997. J. Pharmacol. Exp. Ther.283, 1151.
Chandrakumar, S., et al., 1992. J. Med. Chem.35, 2928.
Tortella, F. 1988. Peptides.9, 1177.
Clark, A., et al., 1986. Eur. J. Pharmacol.128, 303.
Chandrakumar, S., et al., 1992. J. Med. Chem.35, 2928.
Tortella, F. 1988. Peptides.9, 1177.
Clark, A., et al., 1986. Eur. J. Pharmacol.128, 303.
Tyr-D-Pen-Gly-Phe-D-Pen (2-5 disulfide bond)
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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