5.08773
PPACK, 2HCl
InSolution, ≥88%
别名:
InSolution PPACK, 2HCl, D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution
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关于此项目
经验公式（希尔记法）:
C21H31ClN6O3 · 2HCl
分子量:
523.88
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥88% (HPLC)
Form:
liquid
Quality level:
Storage condition:
OK to freeze
avoid repeated freeze/thaw cycles
protect from light
avoid repeated freeze/thaw cycles
protect from light
产品名称
PPACK, 2HCl, InSolution, ≥88%
assay
≥88% (HPLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
protect from light
storage temp.
−70°C
Quality Level
Biochem/physiol Actions
Reversible: no
Disclaimer
Toxicity: Standard Handling (A)
General description
D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone (PPACK) is a potent and specific inhibitor of thrombin with ideal, unbiased properties for use as an anticoagulant in blood gas, electrolyte, and iCa analyses.
Other Notes
Rosado, J. A., et al. 2002. J. Biol. Chem.277, 42157.
Odake S., et al. 1995. J. Enzyme Inhib.9, 17.
Arni, R.K., et al. 1993. Biochemistry32, 4727.
Yamashita, T., et al. 1993. Thromb. Res.69, 93.
Schmaier, A.H., et al. 1992. Thromb. Res.67, 479.
Collen, D., et al. 1982. J. Lab. Clin. Med.99, 76.
Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.
Kettner, C., and Shaw, E. 1979. Thromb. Res.14, 969.
Odake S., et al. 1995. J. Enzyme Inhib.9, 17.
Arni, R.K., et al. 1993. Biochemistry32, 4727.
Yamashita, T., et al. 1993. Thromb. Res.69, 93.
Schmaier, A.H., et al. 1992. Thromb. Res.67, 479.
Collen, D., et al. 1982. J. Lab. Clin. Med.99, 76.
Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.
Kettner, C., and Shaw, E. 1979. Thromb. Res.14, 969.
Packaging
Packaged under inert gas
Physical form
A 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl (Cat. No. 520222) in H₂O.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
法规信息
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此项目有
M E Lyon et al.
Clinical chemistry, 41(7), 1038-1041 (1995-07-01)
D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone (PPACK), a selective thrombin inhibitor, was evaluated as an alternative anticoagulant to lithium heparin (LiHep) for blood gas and whole-blood electrolyte analyses. Initial studies in serum revealed a negative proportional bias for ionized calcium (iCa) concentration measured
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