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经验公式(希尔记法):
C15H18ClO4 · Na
化学文摘社编号:
分子量:
320.74
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
产品名称
Etomoxir, InSolution, ≥98%, 50 mM aqueous solution, shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity
SMILES string
[Na+].Clc1ccc(cc1)OCCCCCC[C@]2(OC2)C(=O)[O-]
InChI
1S/C15H19ClO4.Na/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;/h5-8H,1-4,9-11H2,(H,17,18);/q;+1/p-1/t15-;/m1./s1
InChI key
RPACBEVZENYWOL-XFULWGLBSA-M
assay
≥98% (HPLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles, protect from light
storage temp.
−70°C
Quality Level
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General description
A cell-permeable, irreversible, and stereospecific compound that is shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 µM and 40 µM, respectively.
Biochem/physiol Actions
Primary Target
CPT1
CPT1
Packaging
Packaged under inert gas
Physical form
A 50 mM (2 mg/118 µL) solution of Etomoxir (Cat. No. 236020) in H₂O.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
Other Notes
Xu, F.Y., et al. 2003. J. Lipid Res.44, 415.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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