5.09705
L-Serine-O-phosphate
别名:
L-Serine-O-phosphate, L-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate
方案
≥98% (HPLC)
质量水平
表单
powder
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
off-white
溶解性
water: 50 mg/mL
储存温度
10-30°C
InChI
1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
InChI key
BZQFBWGGLXLEPQ-REOHCLBHSA-N
一般描述
A potent agonist for group III mGlu receptor subtype 4, 6, and 8 (EC50 = 1-4, 3, and 2 µM for mGlu4, mGlu6, mGlu8, respectively); but not for subtype 7 (EC50 = 160-1200 µM). Inhibits proliferation and enhances neuronal differentiation in progenitor cells. Widely used to study presynaptic inhibitory modulation of the excitatory glutamatergic transmission at retina and central nervous systems.
Please note that the molecular weight for this compound is batch-specific due to variable water content.
Please note that the molecular weight for this compound is batch-specific due to variable water content.
生化/生理作用
Primary Target
mGlu₄, mGlu₆, mGlu₈
mGlu₄, mGlu₆, mGlu₈
包装
Packaged under inert gas
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Eriksen, L., et al. 1995. Br. J. Pharmacol.116, 3279.
Thoreson, W., et al. 1995. Brain Res.676, 93.
Bruno, V., et al. 1996. Eur. J. Pharmacol.310, 61.
Saxe, J., et al. 2007. Chem. Biol.14, 1019.
Nakajima, Y., 1993. J. Biol. Chem.268, 11868.
Thoreson, W., et al. 1995. Brain Res.676, 93.
Bruno, V., et al. 1996. Eur. J. Pharmacol.310, 61.
Saxe, J., et al. 2007. Chem. Biol.14, 1019.
Nakajima, Y., 1993. J. Biol. Chem.268, 11868.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
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