Merck
CN
所有图片(1)

文件

516705

Sigma-Aldrich

o-Phenanthroline

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells.

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别名:
o-Phenanthroline, 1,10-Phenanthroline Monohydrate
经验公式（希尔记法）:
C12H8N2 · xH2O
CAS号:
5144-89-8
分子量:
180.21 (anhydrous basis)
MDL编号:
MFCD00149973

质量水平

100

检测方案

≥99% (titration)

形式

solid

manufacturer/tradename

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

white to cream

溶解性

DMSO: 100 mg/mL
ethanol: 25 mg/mL
water: 3 mg/mL

运输

ambient

储存温度

10-30°C

InChI

1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2

InChI key

PPQJCISYYXZCAE-UHFFFAOYSA-N

一般描述

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a general matrix metalloproteinase inhibitor. Forms a red chelate with Fe2+ that absorbs maximally at 510 nm. Can be used as a photometric reagent for iron.
A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a metalloprotease inhibitor. Inhibits glioma invasion in vitro.

生化/生理作用

Cell permeable: no
Primary Target
Metalloprotease inhibitor
Product does not compete with ATP.
Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Toxic (F)

其他说明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Stix, B., et al. 2001. Am. J. Pathol.159, 561.
Bolzan, A.D., et al. 2000. Mutat. Res.447, 221.
Wang, Y., et al. 1999. J. Biol. Chem.274, 33043.
Harayama, T., et al. 1999. Jpn. J. Can. Res.90, 942.
Krane, S.M., et al. 1996. J. Biol. Chem.271, 28509.
Uhm, J.H., et al. 1996. Clin. Exp. Metastasis14, 421.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Skull and crossbonesEnvironment
GHS06,GHS09

警示用语：

Danger

危险声明

H301 - H410

危险分类

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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