524736
Phosphodiesterase 4B2, His•Tag®, Human, Recombinant, S. frugiperda
别名:
PDE4B2, cAMP-Specific Phosphodiesterase 4B2
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关于此项目
NACRES:
NA.54
UNSPSC Code:
12352202
Specific activity:
≥0.25 U/μL
Recombinant:
expressed in baculovirus infected Spodoptera frugiperda cells
recombinant
expressed in baculovirus infected Spodoptera frugiperda cells
form
liquid
specific activity
≥0.25 U/μL
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
shipped in
wet ice
storage temp.
−70°C
Quality Level
General description
Full-length, recombinant, human phosphodiesterase 4B2 (accession no. L20971) fused at the N-terminus to a His•Tag sequence and expressed in S. frugiperda using a baculovirus expression system. Plays a significant role in the regulation of inflammatory cell activation. PDE4B2 is a predominant isoform in neutrophils and monocytes. Supplied as a partially purified, catalytically active preparation.
Physical form
In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Other Notes
Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol.538, 39.
Smith, P.G., et al. 2005 Blood105, 308.
Baroja, M.L., et al. 1999. J. Immunol.162, 2016.
Smith, P.G., et al. 2005 Blood105, 308.
Baroja, M.L., et al. 1999. J. Immunol.162, 2016.
One unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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