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Merck
CN

525185

Sigma-Aldrich

m-3M3FBS

≥95% (HPLC), phospholipase C activator, solid

别名:

Phospholipase C Activator, m-3M3FBS, m-3M3FBS, 2,4,6-Trimethyl-N-( m-3-trifluoromethylphenyl)benzenesulfonamide, m-3M3FBS, 2,4,6-Trimethyl-N-(m-3-trifluoromethylphenyl)benzenesulfonamide

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关于此项目

经验公式（希尔记法）:
C16H16F3NO2S
CAS Number:
200933-14-8
分子量:
343.36
MDL编号:
MFCD00095824
UNSPSC代码:
51111800
NACRES:
NA.77

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Product Name

Phospholipase C Activator, m-3M3FBS, The Phospholipase C Activator, m-3M3FBS, also referenced under CAS 200933-14-8, controls the biological activity of Phospholipase C. This small molecule/inhibitor is primarily used for Activators/Inducers applications.

质量水平

100

方案

≥95% (HPLC)

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

off-white

溶解性

DMSO: 7 mg/mL

运输

ambient

储存温度

2-8°C

SMILES字符串

FC(F)(F)c1cc(ccc1)N[S](=O)(=O)c2c(cc(cc2C)C)C

InChI

1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3

InChI key

ZIIUUSVHCHPIQD-UHFFFAOYSA-N

相关类别

一般描述

A cell-permeable and specific activator of phospholipase C (PLC). Reported to stimulate PLC-mediated intracellular Ca2+ release, inositol phosphate production, and superoxide generation in various cell types. Activates all PLC isotypes (β2, β3, γ1, &gamma2, and δ1) in vitro, but does not exhibit any effect on heterotrimeric G proteins, PI 3-kinase, or phospholipase D.
A novel sulfonamide compound that acts as a cell-permeable and specific activator of phospholipase C (PLC). Shown to stimulate the PLC-mediated intracellular Ca2+ release, inositol phosphates production, and superoxide generation in various cell types. It activates all PLC isotypes (β2, β3, γ1, γ2, and δ1) in vitro, but not heterotrimeric G proteins, PI 3-kinase, or PLD.

生化/生理作用

Cell permeable: yes
Primary Target
Phospholipase C (PLC)
Product does not compete with ATP.
Reversible: no

包装

Packaged under inert gas

制备说明

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.

其他说明

Bae, Y.S., et al. 2003. Mol. Pharmacol.63, 1043.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Carcinogenic / Teratogenic (D)

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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