525276
Phosphoramidon, Disodium Salt
Inhibits some metalloendopeptidases.
别名:
Phosphoramidon, Disodium Salt, N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan, 2Na
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关于此项目
经验公式（希尔记法）:
C23H32N3O10P · 2Na
分子量:
587.47
NACRES:
NA.77
UNSPSC Code:
12352202
Form:
lyophilized solid
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
Quality Segment
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
color
white
solubility
DMSO: 10 mg/mL, methanol: soluble, water: soluble
shipped in
ambient
storage temp.
2-8°C
General description
Effective concentration: 1-10 µM.
Inhibits some metalloendopeptidases. Highly specific inhibitor of thermolysin. Inhibits the conversion of big endothelin-1 to endothelin (IC50 = 4.6 µM).
Biochem/physiol Actions
Cell permeable: no
Primary Target
thermolysin
thermolysin
Product does not compete with ATP.
Reversible: no
Target IC50: 4.6 µM against the conversion of big endothelin-1 to endothelin
Analysis Note
Single spot by TLC
Other Notes
Balwierczxak, J.L., et al. 1995. Biochem. Pharmacol. 49, 291.
Howell, S., et al. 1993. Biochem. J. 290, 159.
Howell, S., et al. 1993. Biochem. J. 290, 159.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable