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Merck
CN

538904

Sigma-Aldrich

Prostaglandin E2

>98% (HPLC), MAP kinase inhibitor, solid

别名:

Prostaglandin E2, PGE₂

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关于此项目

经验公式(希尔记法):
C20H32O5
化学文摘社编号:
分子量:
352.47
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.77
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产品名称

Prostaglandin E2, Involved in vasodilator actions of kinins such as bradykinin.

质量水平

描述

Merck USA index - 14, 7877

方案

>98% (HPLC)

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

white to light yellow

溶解性

acetone: soluble
ethanol: soluble
ethyl acetate: soluble
methanol: soluble

运输

wet ice

储存温度

−20°C

SMILES字符串

OC1C(C(C(=O)C1)C\C=C\CCCC(=O)O)\C=C\C(O)CCCCC

InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4+,13-12+

InChI key

XEYBRNLFEZDVAW-RTYMFESYSA-N

一般描述

Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.

生化/生理作用

Cell permeable: no
Primary Target
Involved in vasodilator actions of kinins such as bradykinin
Product does not compete with ATP.
Reversible: no
Target IC50: 25-50 µM inhibiting MAP kinase in rat mesangial cells

其他说明

Li, X., et al. 1995. Am. J. Physiol.269, C986.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Harmful (C)

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


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