Native protein C from human plasma. Sold as a zymogen. Markedly prolongs kaolin-cephalin clotting time of normal plasma. Activated by α-thrombin to serine protease-activated protein C. In its active form, it is a potent anticoagulant that acts through selective inactivation of Factors Va and VIIIa.

In 100 mM NaCl, 20 mM Tris-HCl, 1 mM benzamidine, pH 7.4.

Following initial thaw, aliquot and freeze (-70°C).

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Esmon, N.L., et al. 1999. Haematologica 84, 363.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Toxicity: Standard Handling (A)