539610
PKCζ/ι Pseudosubstrate Inhibitor
The PKCζ/ι Pseudosubstrate Inhibitor controls the biological activity of PKCζ/ι. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
PKCζ/ι Pseudosubstrate Inhibitor, SIYRRGARRWRKL, Protein Kinase C ζ/ι Pseudosubstrate Inhibitor, SIYRRGARRWRKL, Protein Kinase Cζ/ι Pseudosubstrate Inhibitor
assay
≥95% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
solubility
glacial acetic acid: 2 mg/mL, water: 2 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
A selective, reversible, and substrate competitive inhibitor of protein kinase Cζ and protein kinase Cι (PKCζ/ι) isozymes.
Non-cell-permeable protein kinase Cζ and protein kinase Cι pseudosubstrate sequence peptide that can be used as a selective, reversible, and substrate competitive inhibitor PKCζ/ι in in vitro kinase assays.
Biochem/physiol Actions
Cell permeable: no
Primary Target
PKCζ
PKCζ
Product does not compete with ATP.
Reversible: yes
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
H-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
Sajan, M.P., et al. 1999. J. Biol. Chem.274, 30495.
Laudanna, C., et al. 1998. J. Biol. Chem.273, 30306.
Standaert, M.L., et al. 1997. J. Biol. Chem.272, 30075.
Laudanna, C., et al. 1998. J. Biol. Chem.273, 30306.
Standaert, M.L., et al. 1997. J. Biol. Chem.272, 30075.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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