540217
PTP LYP Inhibitor
The PTP LYP Inhibitor controls the biological activity of PTP LYP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
PTP LYP Inhibitor, (2-pyridine)(Ph)₂P-Au-Cl, HePTP Inhibitor III, PTP Inhibitor XXVIII, PTP-PEST Inhibitor
质量水平
方案
≥95% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
white
溶解性
DMSO: 50 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A cell-permeable, Au(I)-phosphine complex that acts as selective inhibitor of lymphoid tyrosine phosphatase (LYP) (IC50= 1.5 µM) and has a ~10-fold selectivity for LYP over PTP-PEST, HePTP, and CD45 in both JTAg cells and primary mouse thymocytes.
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Karver, M.R., et al. 2009. J. Med. Chem.52, 6912.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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