Merck
CN
  • 557450
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557450

Sigma-Aldrich

钌红-CAS 11103-72-3-Calbiochem

A blocker of transmembrane Ca2+ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening.

All Photos(1)
Synonym(s):
钌红- CAS 11103-72-3 - Calbiochem, 氨化氯氧化钌，RR
Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
12790-48-6
NACRES:
NA.77

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Carbonyl cyanide 3-chlorophenylhydrazone ≥97% (TLC), powder

Sigma-Aldrich

C2759

氰化羰基-3-氯苯腙

≥97% (TLC), powder

质量水平

100

形式

solid

manufacturer/tradename

Calbiochem®

储存条件

OK to freeze
desiccated

颜色

red-black

溶解性

ammonia: soluble
water: soluble

运输

ambient

储存温度

10-30°C

一般描述

一种跨膜Ca2+通量阻滞剂（IC50 = 7 µM），可减弱辣椒素诱导的阳离子通道开放。抑制从对兰尼碱敏感的细胞内Ca2+贮藏中，Ca2+-诱导的Ca2+释放。抑制K+-刺激的儿茶酚胺分泌(IC50 = 6 µM)。
钌：≥35%

包装

250 mg in Glass bottle

生化/生理作用

主靶
跨膜Ca2+通量的阻断剂
产物不与ATP竞争。
可逆：否
细胞可渗透性：否
靶标IC50：7 µM阻断跨膜Ca2+通量；6 µM抑制K+-刺激的儿茶酚胺分泌

警告

毒性：有害（C）

其他说明

Merck Index 13, 8379.
Phillippe, M. and Basa, A. 1996.Biochem.Biophys.Res. Commun.221, 656.
Buratti, R., et al. 1995.Biochem.Biophys.Res. Commun.213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995.J. Pharmacol.Exp.Ther.273, 940.
Gomis, A., et al. 1994.Biochem.Pharmacol.47, 225.
Stjame, P., et al. 1994.Acta Otolaryngol.114, 651.
Ma, J. 1993.J. Gen.Physiol.102, 1031.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

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