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关于此项目
经验公式(希尔记法):
C25H35NO9
化学文摘社编号:
分子量:
493.55
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, protect from light
产品名称
利阿诺定,高纯度, Naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum.
description
Merck USA index - 14, 8307
Quality Level
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 1 mg/mL, methanol: 20 mg/mL
shipped in
ambient
storage temp.
10-30°C
SMILES string
[nH]1c(ccc1)C(=O)O[C@H]2[C@@]3([C@]4([C@]65O[C@]([C@]4([C@@]2(O)C(C)C)C)(C[C@]3([C@]6(CC[C@@H]([C@H]5O)C)O)C)O)O)O
InChI
1S/C25H35NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12-13,15,17,26-27,29-33H,8-9,11H2,1-5H3/t13-,15+,17+,18-,19-,20-,21-,22+,23+,24+,25+/m0/s1
InChI key
JJSYXNQGLHBRRK-YSOSZROBSA-N
General description
阻止肌浆网释放Ca2+的天然生物碱。对Ca2+在肌肉中的运输和作用有许多复杂的影响。纯化自兰尼碱混合物。
Biochem/physiol Actions
主要靶标
Ca2+在肌肉中的运输和作用
Ca2+在肌肉中的运输和作用
产物不与ATP竞争。
可逆:否
细胞可渗透性:否
Preparation Note
复溶后冷藏(4°C)。贮备溶液在4°C下可稳定保存至多1个月。
Other Notes
Sorrentino, V., and Volpe, P. 1993.Trends Pharmacol.Sci.14, 98.
Sabbadini, R., et al. 1992.J. Biol. Chem.267, 15475.
Feher, J.J., and Lipford, G.B.1985.Biochim.Biophys.Acta813, 77.
Marban, E., and Wier, W.G. 1985.Circ.Res.56, 133.
Sukto, J.L., et al. 1985.Fed.Proc.44, 2984.
Sabbadini, R., et al. 1992.J. Biol. Chem.267, 15475.
Feher, J.J., and Lipford, G.B.1985.Biochim.Biophys.Acta813, 77.
Marban, E., and Wier, W.G. 1985.Circ.Res.56, 133.
Sukto, J.L., et al. 1985.Fed.Proc.44, 2984.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性:有害(C)
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Egor A Turovsky et al.
Biology, 10(8) (2021-08-28)
To date, there are practically no data on the mechanisms of the selenium nanoparticles action on calcium homeostasis, intracellular signaling in cancer cells, and on the relationship of signaling pathways activated by an increase in Ca2+ in the cytosol with
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 559276-500UG | 04055977192353 |

