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567570

Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp.

Name: Spectinomycin, Dihydrochloride, Pentahydrate, <i>Streptomyces </i>sp.
Brand: MM

broad spectrum aminoglycoside antibiotic, solid

别名:

Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp.

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关于此项目

经验公式（希尔记法）:

C₁₄H₂₄N₂O₇ · 2HCl · 5H₂O

化学文摘社编号:

22189-32-8

分子量:

495.35

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00150886

Form:

solid

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属性

产品名称

Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp., A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure.

Quality Segment

100

form

solid

manufacturer/tradename

Calbiochem^®

color

white to off-white

shipped in

ambient

storage temp.

2-8°C

SMILES string

[Cl-].[Cl-].[N+H2]([C@@H]1[C@H]2O[C@@]3([C@H](O[C@@H]2[C@H]([C@@H]([C@@H]1O)[N+H2]C)O)O[C@@H](CC3=O)C)O)C.O.O.O.O.O

InChI

1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1

InChI key

DCHJOVNPPSBWHK-UXXUFHFZSA-N

说明

General description

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire’s disease) kinase and expressed in E. coli. Potency: ≥500 µg/mg.

Biochem/physiol Actions

Primary Target
Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure

Other Notes

Thompson, P.R., et al. 1998. J. Biol. Chem. 273, 14788.
Noah, J., and Wollenzien, P. 1997. Nucleic Acids Symp. Ser. 36, 178.
Suter, T.M., et al. 1997. Antimicrob. Agents Chemother. 41, 1385.
Thom, G., and Prescott, C.D. 1997. Bioorg. Med. Chem. 5, 1081.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c