567737
S1P4 Receptor Antagonist, CYM50358
The S1P4 Receptor Antagonist, CYM50358 controls the biological activity of S1P4 Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications.
别名:
S1P4 Receptor Antagonist, CYM50358, CYM50358
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式（希尔记法）:
C20H18Cl2N2O2
化学文摘社编号:
分子量:
389.28
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
DMSO: 100 mg/mL, clear, colorless
运输
ambient
储存温度
2-8°C
SMILES字符串
CC1=CC(=CC(=C1NC(=O)C2=CC=C(O2)C3=C(C=CC(=C3)Cl)Cl)C)CN
InChI
1S/C20H18Cl2N2O2/c1-11-7-13(10-23)8-12(2)19(11)24-20(25)18-6-5-17(26-18)15-9-14(21)3-4-16(15)22/h3-9H,10,23H2,1-2H3,(H,24,25)
InChI key
QWJOPXDAQCDRRM-UHFFFAOYSA-N
一般描述
An arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50 = 25 nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4 µM, 3.9 µM, 5.5 µM, and 25 µM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively).
包装
Packaged under inert gas
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Guerrero, M., et al. 2011. Bioorg. Med. Chem. Lett.21, 3632.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Regulatory Review (Z)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持