572631
SU5402
InSolution
别名:
InSolution SU5402, SU5402
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关于此项目
线性分子式:
C17H16N2O3
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
liquid
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
Quality Segment
assay
≥95% (HPLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
storage temp.
−70°C
General description
Inhibits the tyrosine kinase activity of FGFR1 (IC50 = 10-20 µM in the presence of 1 mM ATP) by interacting with the catalytic domain of FGFR1. Also inhibits aFGF-induced phosphorylation of ERK1 and ERK2 (IC50 = 10-20 µM). In contrast to SU4984, it acts only as a weak inhibitor of tyrosine phosphorylation of the PDGF receptor. Does not inhibit the phosphorylation of insulin receptor and exhibits no inhibitory effect on EGF receptor kinase.
Packaging
Packaged under inert gas
Physical form
A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 572630) in DMSO.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Other Notes
Mohammadi, M., et al. 1997. Science 276, 955.
Legal Information
Not available for sale in the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
存储类别
10 - Combustible liquids
怎么回事？
WGK 1
闪点 (F)
188.6 °F - (refers to pure substance)
闪点 (°C)
87 °C - (refers to pure substance)