573099
Stattic
≥95% (HPLC), STAT3 inhibitor, solid
别名:
STAT3抑制剂V，Stattic
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关于此项目
产品名称
STAT3抑制剂V，Stattic, STAT3 Inhibitor V, Stattic, CAS 19983-44-9, is a cell-permeable inhibitor of STAT3 cellular function that targets the STAT3-SH2 domain and prevents its association with upstream Kinases.
Quality Segment
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
pale yellow
solubility
DMSO: 10 mg/mL, ethanol: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
[S]1(=O)(=O)c2c(ccc(c2)[N+](=O)[O-])C=C1
InChI
1S/C8H5NO4S/c10-9(11)7-2-1-6-3-4-14(12,13)8(6)5-7/h1-5H
InChI key
ZRRGOUHITGRLBA-UHFFFAOYSA-N
General description
Biochem/physiol Actions
STAT3
Packaging
Preparation Note
Other Notes
Legal Information
Disclaimer
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
相关内容
Pathways and Biomarkers of JAK/STAT Signaling
The Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway plays an important role in cell proliferation, cell differentiation, cell migration, and cell death. It is the principal signaling mechanism for a variety of cytokines and growth factors. Constitutive activation or dysregulation of JAK/STAT signaling can result in inflammatory disease, erythrocytosis, gigantism, and leukemia.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 573099-25MG | 07790788051754 |