α-Synuclein A53T, Human, Recombinant, E. coli

Recombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. α-synuclein is an acidic neuronal protein of 140 amino acids that has been implicated in the pathogenesis of Parkinson′s disease and related neurodegenerative disorders. α-Synuclein (A53T) is a point mutant of the α-synuclein gene that has been linked to autosomal dominant early onset Parkinson′s Disease (PD). The apparent molecular weight on SDS-PAGE is ~19-20 kDa.

In 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.

Following initial thaw, aliquot and freeze (-20°C).

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Toxicity: Standard Handling (A)