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Merck
CN

581004

Telomerase Inhibitor III, Sodium Salt

The Telomerase Inhibitor III, Sodium Salt controls the biological activity of Telomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.

别名:

TAG-6, 5ʹ-d(TTAGGG)-3ʹ

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关于此项目

UNSPSC Code:
12352200
Form:
lyophilized
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
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Quality Segment

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

solubility

water: soluble

shipped in

wet ice

storage temp.

−70°C

General description

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomere mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM. Note: 150 nmol = 285 µg.
M.W. ~1900.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Telomerase activity in cell lysates
Product competes with ATP.
Reversible: no

Packaging

Packaged under inert gas

Other Notes

5′-d(TTAGGG)-3′
Mata, J.E., et al. 1997. Toxicol. Appl. Pharmacol. 144, 189.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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