biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
form
liquid
does not contain
preservative
species reactivity
human, mouse
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
General description
Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~125 kDa telomerase (TERT) protein.
Recognizes the ~125 kDa telomerase (TERT) protein.
This Anti-Telomerase (Ab-1) Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation, Paraffin Sections for the detection of Telomerase (Ab-1).
Immunogen
Human
a synthetic peptide corresponding to amino acids from an internal region of the catalytic subunit of human telomerase reverse transcriptase (hTERT)
Application
Immunoblotting (1:100, see comments)
Immunoprecipitation (1:40, see comments)
Paraffin Sections (1:250-1:1000, see comments)
Immunoprecipitation (1:40, see comments)
Paraffin Sections (1:250-1:1000, see comments)
Physical form
Undiluted serum.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Antibody works only weakly in paraffin-embedded tissue sections. Nuclear extracts are recommended for immunoblotting and immunoprecipitation. Variables associated with assay conditions will dictate the optimal working dilution.
Fu, W., et al. 2000. J. Mol. Neurosci. 14, 3.
Kharbanda, S., et al. 2000. Curr. Biol. 10, 568.
Vaziri, H., et al. 1999. Mol. Cell. Biol. 19, 2373.
Kharbanda, S., et al. 2000. Curr. Biol. 10, 568.
Vaziri, H., et al. 1999. Mol. Cell. Biol. 19, 2373.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Daisuke Ogawa et al.
Circulation research, 98(7), e50-e59 (2006-03-25)
Activation of the peroxisome proliferator-activated receptor (PPAR) gamma, the molecular target for insulin sensitizing thiazolidinediones used in patients with type 2 diabetes, inhibits vascular smooth muscle cell (VSMC) proliferation and prevents atherosclerosis and neointima formation. Emerging evidence indicates that telomerase
Sheeba Jacob et al.
Cancer biology & therapy, 17(4), 439-448 (2016-03-24)
Telomerase activation is one of the key mechanisms that allow cells to bypass replicative senescence. Telomerase activity is primarily regulated at the level of transcription of its catalytic unit- hTERT. Prostate cancer (PCa), akin to other cancers, is characterized by
Eva-Maria Fabricius et al.
International journal of oncology, 35(6), 1377-1394 (2009-11-04)
In previous studies we demonstrated telomerase activity in frozen tissues from BCC and their tumor-free margins by the PCR ELISA. In this study we examined in the same frozen sections immunohistochemical presence of hTERT in the nucleus. After fixation in